Evidence of overload, dissolution and breakage of MMVF 10 fibres in the RCC chronic inhalation study

This paper describes (i) the evidence revealing the biological mechanisms underlying data from inhalation experiments at the Research and Consulting Company (RCC) (Hesterberg et al. 1993); and (ii) the quantitative evaluation of the kinetic rates of these mechanisms using a mathematical model developed at the Institute of Occupational Medicine (IOM) (Tran et al. 1994).

Publication Number: P/96/06

First Author: Tran CL

Other Authors: Jones AD , Donaldson K

Publisher: Elsevier,Reed Elsevier Group, 1-3 Strand, London, WC2N 5JR, UK,

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